Isgor B.S., Isgor Y.G., "Effect of Alpha-1-Adrenoceptor Blocker on Cytosolic Enzyme Targets for Potential use in Cancer Chemotherapy", International Journal of Pharmacology (ISI), 8(5): 333-343 pp., 2012 , DOI: 10.3923/ijp.2012.333.343

Text Box: The drug development efforts are not economical in terms of time and budgets. This is due to overwhelming testing procedures of compounds to be identified with reasonable toxicity to human. 
For more effective therapeutic benefits of the drugs in the market, instead of searching for novel one, it is more reasonable to analyze novel targets of the drugs already available in the market . 
The study is the first example of evaluation of doxazosine, the well know antihypertensive drug, for novel targets in cell to develop combined therapeutics for cancer chemotherapy.